Actilyse 20mg Injection

ALTEPLASE
₹20,773.65 ₹23,906.25 (You Save ₹3,133)

1 Vial(s)

Sourced from: BOEHRINGER INGELHEIM INDIA PVT LTD
13% OFF
★★★★★ 4.8 On Google
₹20,773.65 MRP: ₹23,906.25 13% OFF

Inclusive of all taxes

1 Vial(s)
₹20,773.65/Unit
Rx Prescription Required
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Dispatch: Tomorrow
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Quick overview

Actilyse 20mg Injection contains ALTEPLASE and is marketed by BOEHRINGER INGELHEIM INDIA PVT LTD. Country of origin: Germany. This pack is 1 Vial(s), priced at ₹20,773.65 inclusive of all taxes (about 13% off MRP). A valid prescription is required to order this medicine. On MedsRight, Actilyse 20mg Injection is organised under the Cardiology speciality and the Heart Disorder condition category.

Know about Actilyse 20mg Injection in 30 seconds

From salt and price to delivery — the essentials in one short read, in about 30 seconds time.

  • Salt composition: ALTEPLASE — that is what goes into Actilyse 20mg Injection as the active part of the medicine. more options with same salt

  • Pack & price: You pay ₹20,773.65 for 1 Vial(s), including all taxes. The MRP printed on the pack is ₹23,906.25 — you save roughly 13% versus that.

  • Per-unit value: Roughly ₹20,773.65 per unit — handy when you want to compare this pack with a bigger or smaller one.

  • Medical speciality: MedsRight files Actilyse 20mg Injection under “Cardiology” — the same kind of department-wise grouping you see in clinics and hospitals. Explore this speciality

  • Condition category: We link it to “Heart Disorder” so you can find it when you shop by health topic, not only by salt or brand. Browse this condition

  • Marketer: BOEHRINGER INGELHEIM INDIA PVT LTD is the company behind this brand pack — the name you will usually see on invoices and packaging.

  • Country of origin: Country of origin for this pack is Germany.

  • Prescription: You will need a valid prescription to buy Actilyse 20mg Injection. Take it only the way your doctor told you.

  • Storage & handling: Keep it like any everyday medicine at room temperature, unless the pack asks for something special (fridge, away from light, etc.).

  • Dispatch: We use Indian Standard Time. Order before 3:00 PM and your parcel is usually lined up to leave the warehouse the next working day (“Tomorrow”). After 3:00 PM, it slips to the following slot (“Day after”).

  • Doorstep delivery: After it leaves the warehouse, most addresses get it in about 3–4 days, depending on pincode and courier. Rural or remote areas can take a bit longer.

  • Availability: It should be possible to add Actilyse 20mg Injection to your cart right now. Stock can run out if many people order at once, so finish checkout if you need it soon.

Detailed Information

Introduction

Actilyse 20mg Injection contains alteplase, a medication known as recombinant tissue plasminogen activator (rt-PA). It is a clot-dissolving medicine used to treat life-threatening conditions caused by blood clots, such as acute ischemic strokes, heart attacks, and pulmonary embolism. When administered promptly after symptom onset, Actilyse works to restore blood flow to affected areas of the body, helping to minimize tissue damage and improve recovery outcomes. This medication is a thrombolytic agent, meaning it actively breaks down existing blood clots by converting enzymes that dissolve the fibrin proteins holding clots together. Time is critical with Actilyse—the sooner it is given after a clot-related event, the better the chance of preventing permanent damage to the brain, heart, or lungs. While Actilyse can be highly effective, it requires careful medical supervision, as it increases bleeding risk and is not suitable for all patients.

Key points

  • Dissolves blood clots to restore blood flow in acute emergencies
  • Used for stroke, heart attack, and lung clots (pulmonary embolism)
  • Most effective when given within specific time windows after symptom onset
  • Requires hospital administration under close medical supervision

Therapeutic Uses

  • Acute ischemic stroke—to dissolve brain clots and restore blood flow to prevent brain damage
  • Heart attack (myocardial infarction)—to dissolve coronary artery clots and restore heart function
  • Acute massive pulmonary embolism—to dissolve blood clots in the lungs and improve oxygen flow

How it Works

Actilyse 20mg Injection works by activating an enzyme called plasminogen and converting it to plasmin. Plasmin then breaks down fibrin, the protein that holds blood clots together. By dissolving the clot, blood flow is restored to the affected area—whether in the brain, heart, or lungs. This rapid restoration of blood circulation minimizes tissue damage and significantly improves the chances of recovery when administered within the critical treatment window.

How to Take

Actilyse 20mg Injection is given intravenously (directly into a vein) by a qualified healthcare professional in a hospital setting. The exact dose, infusion rate, and treatment plan depend on your specific condition, age, weight, and medical history. Your doctor will determine the appropriate dosing protocol.

Instructions

  • Administration must occur in a hospital or emergency care facility with continuous cardiac monitoring
  • Your healthcare provider will insert an IV line and administer the medication according to your condition
  • Medical staff will monitor your vital signs and bleeding status throughout and after treatment
  • Follow all post-treatment instructions and attend follow-up appointments as scheduled

Timing

Administered immediately in a hospital emergency setting; timing is critical for effectiveness

Missed dose

Actilyse must be given within specific time windows (typically 3-4.5 hours for stroke). If this window is missed, the medication will not be administered. Do not attempt to make up for a missed dose.

Overdose

Overdose is unlikely as Actilyse is administered by medical professionals in controlled doses. However, any signs of excessive bleeding (blood in urine, vomit, stool, or persistent nosebleeds) require immediate medical attention.

Side Effects

  • Bleeding complications—including bleeding in the brain, gastrointestinal tract, or at the injection site
  • Low blood pressure (hypotension) or chest pain
  • Allergic reactions or hypersensitivity responses
  • Irregular heartbeat (cardiac arrhythmias) or fluid accumulation in the lungs
  • Bleeding from damaged blood vessels at the site of the clot

Safety Advice

Pregnancy

Consult Doctor

Limited data exists on Actilyse use during pregnancy. However, in critical, life-threatening situations (such as a stroke during pregnancy), the benefits of clot dissolution may outweigh potential risks to the fetus.

Tip: Pregnant women experiencing stroke or heart attack symptoms should seek emergency medical care immediately. Your doctor will carefully evaluate the severity of your condition and discuss the risks and benefits of treatment with you.

Breastfeeding

Consult Doctor

It is not known whether Actilyse passes into breast milk. Since this medication is given in emergency situations and requires hospital admission, breastfeeding interruption during treatment is typically necessary.

Tip: If you are breastfeeding and require Actilyse treatment, discuss with your healthcare provider about the safety of resuming breastfeeding after treatment.

Liver Disease

Safe

Actilyse is generally considered safe in patients with liver disease, though the liver plays a role in medication clearance. Patients with severe liver impairment require careful monitoring.

Tip: Inform your doctor if you have any liver disease or liver function problems. Your medical team will monitor your condition closely during and after treatment.

Kidney Disease

Consult Doctor

The kidneys help eliminate Actilyse from the body. Patients with severe kidney impairment may require special consideration and monitoring.

Tip: Inform your doctor if you have kidney disease or reduced kidney function. Dosing and monitoring may be adjusted accordingly.

Alcohol

Unsafe

Alcohol consumption while taking Actilyse significantly increases bleeding risk and may negatively affect the cardiovascular system, potentially reducing the medication's effectiveness.

Tip: Avoid all alcohol consumption during Actilyse treatment and for the duration of hospitalization. Discuss alcohol use with your healthcare provider before and after treatment.

Driving

Unsafe

Actilyse can cause side effects such as dizziness, lightheadedness, blurred vision, and irregular heart rhythms that may impair your ability to drive safely. Additionally, you will be hospitalized during treatment.

Tip: Do not drive or operate machinery while receiving Actilyse treatment. Avoid driving until you have fully recovered and your doctor confirms it is safe to do so.

FAQs

Is Actilyse 20mg injection effective in all cases of stroke or blood clots?
Actilyse 20mg Injection is most effective when administered within specific time windows after symptom onset—typically 3 to 4.5 hours for ischemic stroke. Effectiveness depends on the type and location of the clot, how quickly treatment begins, and individual patient factors. Not all stroke or blood clot patients are candidates for this medication; your doctor will assess your condition to determine if Actilyse is appropriate for you.
Are there any contraindications for using Actilyse 20mg injection?
Yes, Actilyse should not be used in patients with allergies to alteplase or its components. It is also contraindicated in patients with significant head trauma or internal injuries within the past three months, active bleeding, recent surgery, or bleeding disorders. Patients over 75 years old have increased bleeding risk. Severe liver or kidney impairment requires careful evaluation. Your doctor will review your complete medical history to determine if Actilyse is safe for you.
Are there any specific tests required before administering Actilyse 20mg injection?
Yes, before receiving Actilyse, your doctor will likely perform several tests including a CT scan of the brain to confirm ischemic stroke (ruling out bleeding), blood clotting tests, liver and kidney function tests, and a complete blood count. Blood pressure monitoring and cardiac assessment may also be conducted. These tests help ensure the medication is safe and appropriate for your condition.
Is there a reversal agent for Actilyse 20mg injection if bleeding occurs?
There is no specific reversal agent for alteplase. If severe bleeding occurs, treatment focuses on supportive care, including stopping the infusion, maintaining blood pressure, and providing blood transfusions if necessary. Fresh frozen plasma may be administered in some cases. This is why Actilyse must only be given in a hospital setting where emergency care is immediately available.
Can Actilyse 20mg injection be used in children or adolescents?
Actilyse is not routinely recommended for use in children. Its use in pediatric patients is limited and only considered in rare, life-threatening situations where other options are unavailable. Any use in children requires specialized pediatric emergency care and careful evaluation by experienced medical professionals.

Drug Interactions

Actilyse 20mg Injection may interact with other medications, particularly those affecting blood clotting or bleeding risk. Inform your doctor about all medications you take, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements before treatment begins.

Major interactions

  • Anticoagulants (warfarin, apixaban, dabigatran) and antiplatelet drugs (aspirin, clopidogrel) increase bleeding risk
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) may increase bleeding complications
  • Other thrombolytic agents should not be combined with Actilyse

Precautions

  • Disclose all current medications to your healthcare provider before treatment
  • Inform your doctor of any recent use of blood thinners or aspirin
  • Report any herbal supplements, particularly those with anticoagulant properties
  • Medication timing around Actilyse administration will be carefully managed by your medical team

Important

Never combine Actilyse with other clot-dissolving medications. Certain drug combinations significantly increase the risk of serious bleeding complications. Your doctor will coordinate all medications to ensure safety.

Storage Details

🌡 Store at room temperature between 20°C to 25°C (68°F to 77°F)

Keep in a cool, dry place away from direct sunlight, heat, and moisture

  • Do not freeze or expose to extreme temperatures
  • Keep the medication in its original container with the label intact
  • Store away from children and pets
  • If stored in a hospital pharmacy, follow institutional storage protocols

Fact Box

Active Ingredient
Alteplase (recombinant tissue plasminogen activator, rt-PA)
Drug Class
Thrombolytic agent (clot-dissolving medication)
Therapeutic Use
Treatment of acute ischemic stroke, heart attack, and pulmonary embolism
Prescription Required
Yes
Route of Administration
Intravenous (IV injection)
Storage Temperature
20°C to 25°C (68°F to 77°F)

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Quality Guaranteed

Guaranteed Temperature-Controlled Handling and Shipping — We maintain strict cold chain compliance for temperature-sensitive medicines from storage to delivery.

1

Carefully Packed

Every order is carefully packaged to maintain the required temperature for cold chain medicines and vaccines.

2

Verified Storage

Our pharmaceutical storage facilities are closely monitored and verified to ensure proper temperature conditions.

3

Insulated Shipping

We use insulated containers and temperature monitors for safe transport of temperature-sensitive medicines.

Rx Prescription Required

This medicine requires a valid prescription from a registered medical practitioner (doctor). As per Indian regulations, prescription-only medicines cannot be sold without a valid Rx.

You will need to upload your prescription during checkout. We accept clear images or PDF of your doctor's prescription.

Consult your doctor before taking any medicine. Never self-medicate with prescription drugs.

Medical Disclaimer

MedsRight is committed to providing consumers with reliable, accurate, and expert-validated healthcare information. All content published on this website is intended solely for general informational and educational purposes. It should not be considered a substitute for professional medical advice, diagnosis, or treatment.

We strongly encourage you to consult a qualified doctor or healthcare professional for guidance regarding any medical condition, symptoms, or medications. Never ignore or postpone seeking professional medical advice because of information you have read on MedsRight.

Our goal is to empower patients with trustworthy information while fully respecting and preserving the integrity of the doctor–patient relationship.

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