Actilyse 50mg Injection

ALTEPLASE
₹37,941.10 ₹49,921.88 (You Save ₹11,981)

1 Vial(s)

Sourced from: BOEHRINGER INGELHEIM INDIA PVT LTD
24% OFF
★★★★★ 4.8 On Google
₹37,941.10 MRP: ₹49,921.88 24% OFF

Inclusive of all taxes

1 Vial(s)
₹37,941.10/Unit
Rx Prescription Required
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Dispatch: Tomorrow
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Quick overview

Actilyse 50mg Injection contains ALTEPLASE and is marketed by BOEHRINGER INGELHEIM INDIA PVT LTD. Country of origin: Germany. This pack is 1 Vial(s), priced at ₹37,941.10 inclusive of all taxes (about 24% off MRP). A valid prescription is required to order this medicine. On MedsRight, Actilyse 50mg Injection is organised under the Cardiology speciality and the Heart Disorder condition category.

Know about Actilyse 50mg Injection in 30 seconds

From salt and price to delivery — the essentials in one short read, in about 30 seconds time.

  • Salt composition: ALTEPLASE — that is what goes into Actilyse 50mg Injection as the active part of the medicine. more options with same salt

  • Pack & price: You pay ₹37,941.10 for 1 Vial(s), including all taxes. The MRP printed on the pack is ₹49,921.88 — you save roughly 24% versus that.

  • Per-unit value: Roughly ₹37,941.10 per unit — handy when you want to compare this pack with a bigger or smaller one.

  • Medical speciality: MedsRight files Actilyse 50mg Injection under “Cardiology” — the same kind of department-wise grouping you see in clinics and hospitals. Explore this speciality

  • Condition category: We link it to “Heart Disorder” so you can find it when you shop by health topic, not only by salt or brand. Browse this condition

  • Marketer: BOEHRINGER INGELHEIM INDIA PVT LTD is the company behind this brand pack — the name you will usually see on invoices and packaging.

  • Country of origin: Country of origin for this pack is Germany.

  • Prescription: You will need a valid prescription to buy Actilyse 50mg Injection. Take it only the way your doctor told you.

  • Storage & handling: Keep it like any everyday medicine at room temperature, unless the pack asks for something special (fridge, away from light, etc.).

  • Dispatch: We use Indian Standard Time. Order before 3:00 PM and your parcel is usually lined up to leave the warehouse the next working day (“Tomorrow”). After 3:00 PM, it slips to the following slot (“Day after”).

  • Doorstep delivery: After it leaves the warehouse, most addresses get it in about 3–4 days, depending on pincode and courier. Rural or remote areas can take a bit longer.

  • Availability: It should be possible to add Actilyse 50mg Injection to your cart right now. Stock can run out if many people order at once, so finish checkout if you need it soon.

Detailed Information

Introduction

Actilyse 50mg injection contains alteplase, a medication also known as recombinant tissue plasminogen activator (rt-PA). It belongs to a class of drugs called thrombolytics, which work by breaking down blood clots that block blood vessels. This medication is primarily used to treat acute ischemic stroke, a serious condition where a blood clot prevents blood flow to the brain. When administered promptly after stroke symptoms begin, Actilyse helps restore blood circulation to the affected brain area, reducing the risk of permanent brain damage and long-term disability.

Actilyse 50mg injection is also used to treat heart attacks and pulmonary embolism (blood clots in the lungs) by dissolving clots and restoring normal blood flow. Like all medications, Actilyse can cause side effects, and your doctor will carefully evaluate whether it is suitable for your specific medical condition before prescribing it.

Key points

  • Thrombolytic agent that breaks down blood clots
  • Used for acute ischemic stroke, heart attack, and pulmonary embolism
  • Most effective when administered within a specific time window after symptoms begin
  • Requires careful medical evaluation due to bleeding risks

Therapeutic Uses

  • Acute ischemic stroke (blood clot blocking blood flow to the brain)
  • Heart attack (acute myocardial infarction)
  • Acute massive pulmonary embolism (blood clots in the lungs)

How it Works

Actilyse 50mg injection works by converting an enzyme called plasminogen into plasmin. This active form of plasmin breaks down fibrin, the protein that forms the structure of blood clots. By dissolving the clot, the medication restores normal blood flow to the affected area, whether in the brain, heart, or lungs. This rapid restoration of blood circulation helps minimize tissue damage and improves the chances of recovery.

How to Take

Actilyse 50mg injection is administered intravenously (directly into a vein) only in a hospital setting under the supervision of trained healthcare professionals. The specific dosage and administration method will be determined by your doctor based on your medical condition, type of blood clot, and overall health status.

Instructions

  • This medication must be given in a hospital or emergency care facility
  • A healthcare professional will inject it directly into your vein
  • Continuous monitoring will be performed during and after administration
  • Treatment timing is critical—it must be given as soon as possible after symptoms begin

Timing

As determined by your healthcare provider based on symptom onset

Missed dose

This medication is administered in a hospital emergency setting and missed doses are not applicable. Your doctor will determine the appropriate timing.

Overdose

Overdose can increase the risk of serious bleeding. If you suspect an overdose, inform your healthcare provider immediately. There is no specific reversal agent, though treatment focuses on stopping the bleeding and providing supportive care.

Side Effects

  • Bleeding (internal or external, including at injection site or in the brain)
  • Allergic or hypersensitivity reactions (rash, itching, swelling)
  • Low blood pressure (hypotension) and dizziness
  • Chest pain or discomfort
  • Fluid buildup in the lungs
  • Irregular heartbeat or arrhythmias

Safety Advice

Pregnancy

Consult Doctor

The safety of Actilyse during pregnancy has not been fully established. However, in life-threatening situations such as acute stroke or heart attack, the potential benefits of treatment may outweigh risks to the developing fetus.

Tip: If you are pregnant and require treatment with Actilyse, your doctor will carefully weigh the critical need for clot dissolution against potential risks to you and your baby before proceeding.

Breastfeeding

Consult Doctor

Limited information is available regarding the passage of alteplase into breast milk. A healthcare professional should assess the risks and benefits before breastfeeding mothers receive this medication.

Tip: Consult your doctor for personalized guidance if you are breastfeeding and require treatment with Actilyse.

Liver

Consult Doctor

Actilyse is cleared from the body through the liver. Patients with severe liver impairment may experience altered drug metabolism and increased risk of complications.

Tip: If you have significant liver disease, inform your doctor before treatment. Your liver function may need to be assessed, and dosage adjustments may be necessary.

Kidney

Consult Doctor

The kidneys play a role in eliminating this medication from the body. Severe kidney impairment may affect drug clearance and increase adverse effect risks.

Tip: Patients with severe kidney disease should inform their doctor. Kidney function testing may be recommended before and during treatment.

Alcohol

Unsafe

Alcohol consumption while taking Actilyse is not recommended. Alcohol can increase bleeding risk, affect cardiovascular function, and potentially increase the risk of dangerous side effects.

Tip: Avoid consuming alcohol completely during treatment with Actilyse. This applies to beer, wine, and spirits of any kind.

Driving

Unsafe

Actilyse can cause dizziness, lightheadedness, blurred vision, and changes in heart rhythm, all of which can impair your ability to drive safely by affecting concentration, alertness, and coordination.

Tip: Do not drive or operate machinery while receiving this medication or immediately after treatment. Avoid driving until your doctor confirms it is safe.

FAQs

Is Actilyse 50mg injection effective in all cases of stroke or blood clots?
Actilyse 50mg injection is most effective when administered within a specific time window after symptoms begin—typically within 3-4.5 hours for acute ischemic stroke. Its effectiveness depends on several factors, including the size and location of the clot, how soon treatment is started, and your overall health. Not all patients are suitable candidates due to contraindications such as recent surgery, bleeding disorders, or severe trauma. Your doctor will determine if Actilyse is the right treatment for your specific condition.
Are there any contraindications for using Actilyse 50mg injection?
Yes, several important contraindications exist. Do not use Actilyse if you have a known allergy to alteplase or any ingredient in the medication. Avoid this medication if you have experienced significant head trauma or internal injuries within the past three months due to increased bleeding risk. Other contraindications include active internal bleeding, recent surgery, severe liver or kidney disease, and uncontrolled high blood pressure. Your doctor will review your complete medical history before prescribing this medication.
Are there any specific tests required before administering Actilyse 50mg injection?
Yes, your doctor will typically perform several tests before administering Actilyse 50mg injection. These may include blood tests to check clotting function, liver and kidney function tests, and imaging studies (such as a CT or MRI scan) to confirm the diagnosis and rule out contraindications like bleeding in the brain. Your doctor will also review your medical history, current medications, and recent surgeries. These evaluations help ensure the medication is safe and appropriate for your condition.
Is there a reversal agent for Actilyse 50mg injection if bleeding occurs?
There is no specific medication that completely reverses the effects of Actilyse if bleeding occurs. However, if serious bleeding develops, your healthcare team will provide supportive care, which may include blood transfusions, fresh frozen plasma, or platelet transfusions to help control bleeding. In some cases, medications called antifibrinolytic agents may be used. Continuous monitoring in a hospital setting allows doctors to detect and manage bleeding complications quickly. This is why treatment must only occur in a fully equipped medical facility.
Can Actilyse 50mg injection be used in children or adolescents?
The use of Actilyse 50mg injection in children and adolescents is limited and not routinely recommended for most conditions. While it may be considered in specific emergency situations such as certain types of stroke or blood clots in young patients, this decision requires specialized pediatric medical expertise. Any use in pediatric patients would be determined by a qualified healthcare provider on a case-by-case basis, weighing the critical need for treatment against potential risks. Always consult a pediatric specialist regarding the appropriateness of this medication for young patients.

Drug Interactions

Actilyse 50mg injection may interact with other medications, potentially reducing its effectiveness or increasing the risk of adverse effects. It is essential to inform your doctor about all medications you are currently taking, including prescription drugs, over-the-counter medicines, vitamins, nutritional supplements, and herbal products before treatment begins.

Major interactions

  • Antiplatelet agents (aspirin, clopidogrel) may increase bleeding risk
  • Anticoagulants (warfarin, heparin) may potentiate bleeding complications
  • Other thrombolytic agents should not be used concurrently

Precautions

  • Always disclose your complete medication history to your healthcare provider
  • Avoid starting new medications during Actilyse treatment without consulting your doctor
  • Inform all healthcare providers that you have received this thrombolytic medication

Important

Do not use Actilyse with other blood clot-dissolving medications. Combining these drugs significantly increases the risk of dangerous bleeding.

Storage Details

🌡 Store between 20°C to 25°C (68°F to 77°F)

Keep in a cool, dry place away from direct sunlight and moisture

  • Do not freeze the medication
  • Keep away from heat and light exposure
  • Store in its original container or as directed by your pharmacist
  • Keep out of reach of children and pets
  • Do not use if the medication appears discolored or contains particles

Fact Box

Active Ingredient
Alteplase (recombinant tissue plasminogen activator, rt-PA)
Drug Class
Thrombolytic agent (blood clot dissolver)
Therapeutic Use
Treatment of acute ischemic stroke, heart attack, and pulmonary embolism
Prescription Required
Yes
Route of Administration
Intravenous injection (hospital use only)
Storage Temperature
20°C to 25°C (68°F to 77°F)

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Quality Guaranteed

Guaranteed Temperature-Controlled Handling and Shipping — We maintain strict cold chain compliance for temperature-sensitive medicines from storage to delivery.

1

Carefully Packed

Every order is carefully packaged to maintain the required temperature for cold chain medicines and vaccines.

2

Verified Storage

Our pharmaceutical storage facilities are closely monitored and verified to ensure proper temperature conditions.

3

Insulated Shipping

We use insulated containers and temperature monitors for safe transport of temperature-sensitive medicines.

Rx Prescription Required

This medicine requires a valid prescription from a registered medical practitioner (doctor). As per Indian regulations, prescription-only medicines cannot be sold without a valid Rx.

You will need to upload your prescription during checkout. We accept clear images or PDF of your doctor's prescription.

Consult your doctor before taking any medicine. Never self-medicate with prescription drugs.

Medical Disclaimer

MedsRight is committed to providing consumers with reliable, accurate, and expert-validated healthcare information. All content published on this website is intended solely for general informational and educational purposes. It should not be considered a substitute for professional medical advice, diagnosis, or treatment.

We strongly encourage you to consult a qualified doctor or healthcare professional for guidance regarding any medical condition, symptoms, or medications. Never ignore or postpone seeking professional medical advice because of information you have read on MedsRight.

Our goal is to empower patients with trustworthy information while fully respecting and preserving the integrity of the doctor–patient relationship.

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