Advagraf 1mg Capsule

TACROLIMUS
₹579.50 ₹937.50 (You Save ₹358)

Sourced from: ASTELLAS PHARMA INC
38% OFF
★★★★★ 4.8 On Google
₹579.50 MRP: ₹937.50 38% OFF

Inclusive of all taxes

₹579.50/Unit
Rx Prescription Required
Salt Composition
TACROLIMUS
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Dispatch: Tomorrow
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Quick overview

Advagraf 1mg Capsule contains TACROLIMUS and is marketed by ASTELLAS PHARMA INC. Country of origin: India. This pack is , priced at ₹579.50 inclusive of all taxes (about 38% off MRP). A valid prescription is required to order this medicine. On MedsRight, Advagraf 1mg Capsule is organised under the Nephrology speciality and the Transplant condition category.

Know about Advagraf 1mg Capsule in 30 seconds

From salt and price to delivery — the essentials in one short read, in about 30 seconds time.

  • Salt composition: TACROLIMUS — that is what goes into Advagraf 1mg Capsule as the active part of the medicine. more options with same salt

  • Pack & price: You pay ₹579.50 for , including all taxes. The MRP printed on the pack is ₹937.50 — you save roughly 38% versus that.

  • Per-unit value: Roughly ₹579.50 per unit — handy when you want to compare this pack with a bigger or smaller one.

  • Medical speciality: MedsRight files Advagraf 1mg Capsule under “Nephrology” — the same kind of department-wise grouping you see in clinics and hospitals. Explore this speciality

  • Condition category: We link it to “Transplant” so you can find it when you shop by health topic, not only by salt or brand. Browse this condition

  • Marketer: ASTELLAS PHARMA INC is the company behind this brand pack — the name you will usually see on invoices and packaging.

  • Country of origin: Country of origin for this pack is India.

  • Prescription: You will need a valid prescription to buy Advagraf 1mg Capsule. Take it only the way your doctor told you.

  • Storage & handling: Keep it like any everyday medicine at room temperature, unless the pack asks for something special (fridge, away from light, etc.).

  • Dispatch: We use Indian Standard Time. Order before 3:00 PM and your parcel is usually lined up to leave the warehouse the next working day (“Tomorrow”). After 3:00 PM, it slips to the following slot (“Day after”).

  • Doorstep delivery: After it leaves the warehouse, most addresses get it in about 3–4 days, depending on pincode and courier. Rural or remote areas can take a bit longer.

  • Availability: It should be possible to add Advagraf 1mg Capsule to your cart right now. Stock can run out if many people order at once, so finish checkout if you need it soon.

Detailed Information

Introduction

Advagraf 1mg Capsule contains tacrolimus, a powerful immunosuppressant medication belonging to a class of drugs called calcineurin inhibitors. This medicine is prescribed to prevent your body from rejecting a transplanted organ—whether it's a liver, kidney, heart, or other vital organ. By controlling your immune system's response, Advagraf helps your body accept and protect the new organ.

This medication works by reducing the activity of T-lymphocytes (immune cells) that would normally attack the transplanted organ. It is always used alongside other immunosuppressive medications as part of a comprehensive transplant rejection prevention plan. Taking Advagraf exactly as your doctor prescribes is essential for long-term transplant success and organ function.

Key points

  • Prevents organ transplant rejection after liver, kidney, heart, or other transplants
  • Works as a calcineurin inhibitor to suppress immune system response
  • Must be taken continuously as prescribed—do not stop without medical guidance
  • Requires regular monitoring and blood tests to ensure effectiveness and safety

Therapeutic Uses

  • Prevent organ rejection in transplant recipients receiving liver, kidney, heart, or other organ transplants
  • Control excessive immune response to help the body accept and maintain the transplanted organ

How it Works

Advagraf 1mg Capsule works by attaching to a protein in your immune cells called FKBP-12. This creates a complex that blocks calcineurin phosphatase, an enzyme responsible for activating T-lymphocytes (immune cells). By inhibiting this enzyme, Advagraf prevents T-cells from activating and multiplying, which reduces your immune system's ability to attack the transplanted organ. This controlled immune suppression allows your body to accept the new organ while still maintaining some protection against infections.

How to Take

Your doctor will determine the correct dose and treatment duration based on your specific condition, transplant type, kidney function, and other health factors. Always swallow your Advagraf capsule whole—never open, crush, break, or chew it, as this can damage the medication's delayed-release mechanism.

Instructions

  • Take Advagraf exactly as prescribed by your transplant physician
  • Swallow the capsule whole with a full glass of water
  • Do not open, crush, break, or chew the capsule
  • Take on an empty stomach for best absorption

Timing

Take on an empty stomach, at least 1 hour before or 2–3 hours after eating

Missed dose

Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Never take a double dose to make up for a missed dose.

Overdose

If you suspect an overdose, contact your doctor or local poison control immediately. Do not delay seeking medical attention.

Side Effects

  • Swelling in arms or legs, hair loss, and itchy skin
  • Constipation or diarrhea, nausea, and vomiting
  • Headache, cough, and anemia (low red blood cell count)
  • Irregular heartbeat, gastrointestinal bleeding, and liver injury
  • Seizures, acute kidney failure, and lung infections or respiratory problems

Safety Advice

Pregnancy

Consult Doctor

Animal studies have shown potential harmful effects on fetal development. However, some transplant recipients may need to continue Advagraf during pregnancy to prevent organ rejection. The decision must be made with your healthcare team, weighing the risks and benefits.

Tip: Inform your doctor immediately if you are pregnant, suspect you may be pregnant, or are planning to conceive before starting or continuing Advagraf. Do not stop taking this medication without medical guidance.

Breastfeeding

Unsafe

Tacrolimus is excreted into breast milk and may cause harmful effects to a nursing infant. The medication can pass through breast milk and potentially affect your baby's immune system development.

Tip: Do not breastfeed while taking Advagraf 1mg Capsule. Discuss alternative feeding methods with your doctor.

Liver Disease

Consult Doctor

Advagraf is processed by the liver. Patients with severe liver disease may require dose adjustments to prevent dangerous accumulation of the medication in their bloodstream.

Tip: Inform your doctor if you have a history of liver disease or liver problems before starting treatment. Your doctor may order liver function tests and adjust your dose accordingly.

Kidney Disease

Consult Doctor

Advagraf can affect kidney function, and patients with pre-existing kidney disease require careful monitoring. Regular kidney function tests are essential to detect any decline early.

Tip: Inform your doctor of any kidney problems before starting treatment. Your doctor will monitor your kidney function with regular blood tests (creatinine and BUN levels).

Lung Disease

Consult Doctor

Limited data is available regarding the use of Advagraf in patients with lung disorders. The medication's effects on respiratory function in these patients are not fully understood.

Tip: Consult your doctor if you have any lung diseases, such as asthma, COPD, or pulmonary fibrosis, before starting Advagraf.

Alcohol

Unsafe

Combining alcohol with Advagraf can cause excessive drowsiness, dizziness, and may worsen liver problems. Alcohol can also interfere with your immune system during transplant recovery.

Tip: Avoid alcohol entirely while taking Advagraf 1mg Capsule.

Driving

Unsafe

Advagraf may cause drowsiness, dizziness, confusion, and vision problems that can impair your ability to drive safely or operate heavy machinery.

Tip: Do not drive or operate machinery if you experience drowsiness, dizziness, or vision changes. Avoid these activities until you know how the medication affects you.

FAQs

What if I missed a dose of Advagraf 1mg Capsule?
Take the missed dose as soon as you remember it. However, if your next scheduled dose is approaching (within a few hours), skip the missed dose and continue with your regular dosing schedule. Never take two doses at once to make up for a forgotten dose, as this increases the risk of side effects and medication levels becoming too high.
What should you not use with Advagraf 1mg Capsule?
Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, and cyclosporine alongside Advagraf, as these can significantly interact with the medication. Also avoid certain antibiotics and antiviral medications without your doctor's approval. Most importantly, do not consume grapefruit or grapefruit juice, as it can dangerously increase tacrolimus levels. Always inform your healthcare provider about all medications, supplements, and herbal products you take before starting treatment.
For what duration do I need to take Advagraf 1mg Capsule after a transplant?
You will need to take Advagraf as a long-term medication, typically for the lifetime of your transplanted organ. Stopping the medication without your doctor's guidance can lead to organ rejection. Your transplant team will monitor your progress and may adjust your dose over time based on your blood levels, kidney function, and overall health. Do not stop taking this medicine without consulting your physician first.
Can Advagraf 1mg Capsule increase the risk of infections?
Yes, because Advagraf suppresses your immune system to prevent transplant rejection, it increases your susceptibility to infections. You may experience more frequent or severe infections, including bacterial, viral, and fungal infections. Inform your doctor immediately if you develop signs of infection such as fever, unusual tiredness, or persistent cough. Before receiving any vaccinations, consult your transplant team, as vaccines may not work effectively while taking this medication.
Can Advagraf 1mg Capsule affect kidney function?
Yes, Advagraf can affect kidney function, and some patients may experience a decline in kidney performance over time. This is why regular monitoring with blood tests measuring creatinine and other kidney function markers is essential. Your doctor will track your kidney function closely and may adjust your dose if needed. Report any changes in urine output or color to your healthcare provider immediately.
Should I follow any dietary restrictions while taking Advagraf 1mg Capsule?
Yes, avoid grapefruit and grapefruit juice entirely, as they can significantly increase tacrolimus levels and raise the risk of side effects. Take Advagraf on an empty stomach—at least 1 hour before or 2 to 3 hours after meals—for optimal absorption. While there are no other strict dietary restrictions, maintain a healthy, balanced diet and discuss any specific dietary concerns with your transplant team or nutritionist.

Drug Interactions

Several medications and foods can interact with Advagraf 1mg Capsule, potentially reducing its effectiveness or increasing the risk of serious side effects. It is critical to inform your healthcare provider about all medications you take, including prescription drugs, over-the-counter medications, herbal supplements, and nutritional products before starting treatment.

Major interactions

  • Grapefruit and grapefruit juice—can significantly increase tacrolimus levels in your blood
  • Mycophenolic acid-containing products
  • Nelfinavir and other antiretroviral medications
  • Sirolimus and cyclosporine (other immunosuppressants)
  • Certain antibiotics and antiviral medications

Precautions

  • Always disclose all current medications to your doctor before starting Advagraf
  • Avoid grapefruit products entirely while taking this medicine
  • Inform your physician if you plan to start any new medications
  • Discuss all herbal and dietary supplements with your healthcare provider

Important

Do not consume grapefruit or grapefruit juice while using Advagraf 1mg Capsule. Grapefruit can dangerously increase tacrolimus levels in your blood, raising the risk of side effects and organ damage. Always consult your doctor before taking any new medications or supplements.

Storage Details

🌡 Store at room temperature (25°C / 77°F)

Keep in a cool, dry place away from direct sunlight and moisture

  • Keep Advagraf out of reach of children and pets
  • Do not store in bathrooms or areas with high humidity
  • Keep in original packaging to protect from light and moisture
  • Do not use if the capsule appears damaged or discolored

Fact Box

Active Ingredient
Tacrolimus 1mg
Drug Class
Calcineurin Inhibitor (Immunosuppressant)
Therapeutic Use
Prevention of organ transplant rejection
Prescription Required
Yes

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Quality Guaranteed

Guaranteed Temperature-Controlled Handling and Shipping — We maintain strict cold chain compliance for temperature-sensitive medicines from storage to delivery.

1

Carefully Packed

Every order is carefully packaged to maintain the required temperature for cold chain medicines and vaccines.

2

Verified Storage

Our pharmaceutical storage facilities are closely monitored and verified to ensure proper temperature conditions.

3

Insulated Shipping

We use insulated containers and temperature monitors for safe transport of temperature-sensitive medicines.

Rx Prescription Required

This medicine requires a valid prescription from a registered medical practitioner (doctor). As per Indian regulations, prescription-only medicines cannot be sold without a valid Rx.

You will need to upload your prescription during checkout. We accept clear images or PDF of your doctor's prescription.

Consult your doctor before taking any medicine. Never self-medicate with prescription drugs.

Medical Disclaimer

MedsRight is committed to providing consumers with reliable, accurate, and expert-validated healthcare information. All content published on this website is intended solely for general informational and educational purposes. It should not be considered a substitute for professional medical advice, diagnosis, or treatment.

We strongly encourage you to consult a qualified doctor or healthcare professional for guidance regarding any medical condition, symptoms, or medications. Never ignore or postpone seeking professional medical advice because of information you have read on MedsRight.

Our goal is to empower patients with trustworthy information while fully respecting and preserving the integrity of the doctor–patient relationship.

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