₹4,702.50 ₹5,625.00 (You Save ₹923)

1 Vial(s)

Sourced from: GLENMARK PHARMACEUTICALS LTD
16% OFF
★★★★★ 4.8 On Google
₹4,702.50 MRP: ₹5,625.00 16% OFF

Inclusive of all taxes

1 Vial(s)
₹4,702.50/Unit
Rx Prescription Required
🚚
Dispatch: Tomorrow
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Quick overview

Akynzeo Injection contains FOSNETUPITANT,PALONOSETRON and is marketed by GLENMARK PHARMACEUTICALS LTD. Country of origin: India. This pack is 1 Vial(s), priced at ₹4,702.50 inclusive of all taxes (about 16% off MRP). A valid prescription is required to order this medicine. On MedsRight, Akynzeo Injection is organised under the Oncology speciality and the Anti Cancer condition category.

Know about Akynzeo Injection in 30 seconds

From salt and price to delivery — the essentials in one short read, in about 30 seconds time.

  • Salt composition: FOSNETUPITANT,PALONOSETRON — that is what goes into Akynzeo Injection as the active part of the medicine. more options with same salt

  • Pack & price: You pay ₹4,702.50 for 1 Vial(s), including all taxes. The MRP printed on the pack is ₹5,625.00 — you save roughly 16% versus that.

  • Per-unit value: Roughly ₹4,702.50 per unit — handy when you want to compare this pack with a bigger or smaller one.

  • Medical speciality: MedsRight files Akynzeo Injection under “Oncology” — the same kind of department-wise grouping you see in clinics and hospitals. Explore this speciality

  • Condition category: We link it to “Anti Cancer” so you can find it when you shop by health topic, not only by salt or brand. Browse this condition

  • Marketer: GLENMARK PHARMACEUTICALS LTD is the company behind this brand pack — the name you will usually see on invoices and packaging.

  • Country of origin: Country of origin for this pack is India.

  • Prescription: You will need a valid prescription to buy Akynzeo Injection. Take it only the way your doctor told you.

  • Storage & handling: Keep it like any everyday medicine at room temperature, unless the pack asks for something special (fridge, away from light, etc.).

  • Dispatch: We use Indian Standard Time. Order before 3:00 PM and your parcel is usually lined up to leave the warehouse the next working day (“Tomorrow”). After 3:00 PM, it slips to the following slot (“Day after”).

  • Doorstep delivery: After it leaves the warehouse, most addresses get it in about 3–4 days, depending on pincode and courier. Rural or remote areas can take a bit longer.

  • Availability: It should be possible to add Akynzeo Injection to your cart right now. Stock can run out if many people order at once, so finish checkout if you need it soon.

Detailed Information

Introduction

Akynzeo Injection is a prescription anti-nausea medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV). It contains two active ingredients—fosnetupitant and palonosetron—that work together to block nausea signals in your brain and gut. This combination approach makes Akynzeo highly effective for cancer patients undergoing chemotherapy and surgical patients, helping them tolerate treatment better and recover more comfortably. The injection is administered intravenously by a healthcare provider in a hospital or clinical setting, typically as a 30-minute infusion before chemotherapy or before anesthesia for surgery.

Key points

  • Fixed-dose combination of fosnetupitant (NK-1 receptor antagonist) and palonosetron (5-HT3 receptor antagonist)
  • Prevents chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting
  • Administered as an intravenous injection by healthcare professionals only
  • More effective than single-agent antiemetics due to dual mechanism of action

Therapeutic Uses

  • Prevention of chemotherapy-induced nausea and vomiting (CINV) in cancer patients receiving chemotherapy
  • Prevention of postoperative nausea and vomiting after surgery and anesthesia

How it Works

Akynzeo Injection works through a dual mechanism of action. Fosnetupitant blocks neurokinin-1 (NK-1) receptors in the brain, while palonosetron blocks serotonin (5-HT3) receptors in the gut and brain. Together, these two medications prevent the signals that trigger nausea and vomiting, providing comprehensive protection against chemotherapy-induced and postoperative nausea. This combination approach is more effective than using a single antiemetic agent alone.

How to Take

Akynzeo Injection is administered exclusively as an intravenous (IV) injection by trained healthcare professionals in a hospital, clinic, or surgical center. It cannot be taken at home or self-administered.

Instructions

  • Your healthcare provider will administer Akynzeo Injection as a 30-minute IV infusion
  • For chemotherapy patients: injection is given before or on the day of chemotherapy treatment
  • For surgery patients: injection is given before or right before anesthesia
  • Do not attempt to self-administer this medication

Timing

Before chemotherapy or immediately before anesthesia for surgery

Missed dose

Contact your healthcare provider if you miss your scheduled injection. Do not attempt to catch up on a missed dose without medical guidance.

Overdose

Overdose is unlikely in a supervised medical setting. If you experience severe symptoms, inform your healthcare provider immediately.

Side Effects

  • Allergic reactions including hives, swollen face, breathing difficulty, and chest pain
  • Headache and dizziness
  • Fatigue and general tiredness
  • Abdominal pain or discomfort

Safety Advice

Pregnancy

Unsafe

Akynzeo Injection may cause harm to the developing baby. The safety of this medication in pregnant women has not been established.

Tip: Do not use Akynzeo Injection if you are pregnant or planning to become pregnant. Consult your doctor immediately if you become pregnant while being treated with this medication.

Breastfeeding

Consult Doctor

It is unclear whether Akynzeo Injection passes into breast milk. The effects on nursing infants are unknown.

Tip: Consult your healthcare provider before breastfeeding while receiving Akynzeo Injection. Your doctor will help you weigh the benefits and risks.

Liver Disease

Consult Doctor

Akynzeo Injection is metabolized by the liver. Patients with liver problems may require dosage adjustments or additional monitoring.

Tip: Inform your healthcare provider if you have any liver disorders or reduced liver function before starting treatment.

Kidney Disease

Consult Doctor

Patients with severe kidney impairment may require dosage adjustments. The effects on kidney function are not fully established.

Tip: Inform your doctor if you have kidney problems or reduced kidney function before receiving this injection.

Lung Disease

Consult Doctor

Safety in patients with lung diseases has not been established. Respiratory complications are possible in certain conditions.

Tip: Consult your healthcare provider if you have any lung diseases or respiratory conditions before starting treatment.

Alcohol

Consult Doctor

The interaction between alcohol and Akynzeo Injection is not fully understood. Alcohol may worsen nausea and vomiting.

Tip: Consult your healthcare provider about alcohol consumption while receiving Akynzeo Injection.

Driving

Consult Doctor

While Akynzeo Injection does not directly impair driving ability, side effects like dizziness, fatigue, or drowsiness may affect your ability to drive safely.

Tip: Avoid driving or operating machinery if you experience side effects such as dizziness, fatigue, or drowsiness after receiving this injection.

Pediatric Use

Consult Doctor

Safety and effectiveness of Akynzeo Injection in children have not been established. This medication is intended for adult use only.

Tip: This medication is not recommended for pediatric patients. Consult your pediatrician for age-appropriate antiemetic options.

FAQs

What are the possible side effects of Akynzeo Injection?
Akynzeo Injection can cause serious allergic reactions such as hives, facial swelling, difficulty breathing, and chest pain. These require immediate medical attention. More common side effects include headache, dizziness, fatigue, and abdominal pain. Most side effects are mild and temporary. Report any concerning or persistent symptoms to your healthcare provider.
What is the working mechanism of an Akynzeo capsule?
Akynzeo works by blocking two different pathways that trigger nausea and vomiting. Fosnetupitant blocks NK-1 receptors in the brain, while palonosetron blocks serotonin (5-HT3) receptors in both the brain and gut. This dual-action approach prevents the chemical signals that cause nausea and vomiting, making it more effective than single-agent antiemetics.
How effective is Akynzeo Injection in preventing CINV?
Akynzeo Injection is highly effective in preventing chemotherapy-induced nausea and vomiting. By combining two different classes of antiemetic medications (NK-1 receptor antagonist and 5-HT3 receptor antagonist), it provides comprehensive control of nausea and vomiting associated with chemotherapy. Effectiveness may vary from person to person based on individual factors and the type of chemotherapy received.
Who should not take a Akynzeo Injection?
Akynzeo Injection should not be used by pregnant women due to potential harm to the baby. It is not recommended for children, as safety in pediatric patients has not been established. Patients with severe allergies to fosnetupitant or palonosetron should not receive this medication. Consult your healthcare provider if you have liver disease, kidney disease, lung disease, or are taking serotonergic medications.
What forms does Akynzeo Injection come in?
Akynzeo is available exclusively as an intravenous (IV) injection for professional administration in medical settings. It is a fixed-dose combination containing fosnetupitant and palonosetron in a single preparation. The injection is typically administered as a 30-minute IV infusion and is not available in oral, tablet, or capsule forms.

Drug Interactions

Akynzeo Injection may interact with several medications, potentially reducing effectiveness or causing unwanted side effects. Inform your healthcare provider about all medications you take, including prescription drugs, over-the-counter medicines, supplements, and herbal products, before receiving this injection.

Major interactions

  • Serotonergic medications (antidepressants like SSRIs, SNRIs, certain pain medications) — may increase risk of serotonin syndrome
  • Other antiemetic medications — may reduce effectiveness or cause duplication of effects
  • Medications metabolized by liver enzymes — may require dosage adjustments

Precautions

  • Disclose all current medications to your healthcare provider before treatment
  • Report any history of serotonin syndrome or sensitivity to serotonergic drugs
  • Inform your provider about herbal supplements, especially St. John's Wort

Important

Serotonin syndrome is a serious condition that can occur when Akynzeo is combined with certain serotonergic medications. Symptoms include agitation, hallucinations, rapid heartbeat, fever, muscle stiffness, and coordination problems. Seek immediate medical attention if you experience these symptoms.

Storage Details

🌡 Store below 25°C (77°F)

Store in a cool, dry place away from direct sunlight and heat

  • Do not freeze Akynzeo Injection
  • Keep out of reach of children and pets
  • Store in original packaging to protect from light

Fact Box

Active Ingredients
Fosnetupitant and Palonosetron
Drug Class
NK-1 receptor antagonist and 5-HT3 receptor antagonist combination (antiemetic)
Therapeutic Use
Prevention of chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV)
Route of Administration
Intravenous (IV) injection
Prescription Required
Yes
Storage
Below 25°C, do not freeze

Change Delivery Location

Quality Guaranteed

Guaranteed Temperature-Controlled Handling and Shipping — We maintain strict cold chain compliance for temperature-sensitive medicines from storage to delivery.

1

Carefully Packed

Every order is carefully packaged to maintain the required temperature for cold chain medicines and vaccines.

2

Verified Storage

Our pharmaceutical storage facilities are closely monitored and verified to ensure proper temperature conditions.

3

Insulated Shipping

We use insulated containers and temperature monitors for safe transport of temperature-sensitive medicines.

Rx Prescription Required

This medicine requires a valid prescription from a registered medical practitioner (doctor). As per Indian regulations, prescription-only medicines cannot be sold without a valid Rx.

You will need to upload your prescription during checkout. We accept clear images or PDF of your doctor's prescription.

Consult your doctor before taking any medicine. Never self-medicate with prescription drugs.

Medical Disclaimer

MedsRight is committed to providing consumers with reliable, accurate, and expert-validated healthcare information. All content published on this website is intended solely for general informational and educational purposes. It should not be considered a substitute for professional medical advice, diagnosis, or treatment.

We strongly encourage you to consult a qualified doctor or healthcare professional for guidance regarding any medical condition, symptoms, or medications. Never ignore or postpone seeking professional medical advice because of information you have read on MedsRight.

Our goal is to empower patients with trustworthy information while fully respecting and preserving the integrity of the doctor–patient relationship.

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