Zyfol Injection 20ml

PROPOFOL
₹72.20 ₹151.94 (You Save ₹80)

1 Vial(s) Of 20ml

Sourced from: THEMIS MEDICARE LTD
52% OFF
★★★★★ 4.8 On Google
₹72.20 MRP: ₹151.94 52% OFF

Inclusive of all taxes

1 Vial(s) Of 20ml
₹72.20/Unit
Rx Prescription Required
Salt Composition
PROPOFOL
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Dispatch: Tomorrow
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Quick overview

Zyfol Injection 20ml contains PROPOFOL and is marketed by THEMIS MEDICARE LTD. Country of origin: India. This pack is 1 Vial(s) Of 20ml, priced at ₹72.20 inclusive of all taxes (about 52% off MRP). A valid prescription is required to order this medicine. On MedsRight, Zyfol Injection 20ml is organised under the Others speciality and the Anaesthetics condition category.

Know about Zyfol Injection 20ml in 30 seconds

From salt and price to delivery — the essentials in one short read, in about 30 seconds time.

  • Salt composition: PROPOFOL — that is what goes into Zyfol Injection 20ml as the active part of the medicine. more options with same salt

  • Pack & price: You pay ₹72.20 for 1 Vial(s) Of 20ml, including all taxes. The MRP printed on the pack is ₹151.94 — you save roughly 52% versus that.

  • Per-unit value: Roughly ₹72.20 per unit — handy when you want to compare this pack with a bigger or smaller one.

  • Medical speciality: MedsRight files Zyfol Injection 20ml under “Others” — the same kind of department-wise grouping you see in clinics and hospitals. Explore this speciality

  • Condition category: We link it to “Anaesthetics” so you can find it when you shop by health topic, not only by salt or brand. Browse this condition

  • Marketer: THEMIS MEDICARE LTD is the company behind this brand pack — the name you will usually see on invoices and packaging.

  • Country of origin: Country of origin for this pack is India.

  • Prescription: You will need a valid prescription to buy Zyfol Injection 20ml. Take it only the way your doctor told you.

  • Storage & handling: Keep it like any everyday medicine at room temperature, unless the pack asks for something special (fridge, away from light, etc.).

  • Dispatch: We use Indian Standard Time. Order before 3:00 PM and your parcel is usually lined up to leave the warehouse the next working day (“Tomorrow”). After 3:00 PM, it slips to the following slot (“Day after”).

  • Doorstep delivery: After it leaves the warehouse, most addresses get it in about 3–4 days, depending on pincode and courier. Rural or remote areas can take a bit longer.

  • Availability: It should be possible to add Zyfol Injection 20ml to your cart right now. Stock can run out if many people order at once, so finish checkout if you need it soon.

Detailed Information

Introduction

Zyfol 20ml injection contains propofol, a general anesthetic medicine used to induce unconsciousness during surgical procedures and medical operations. It works by temporarily putting you to sleep so that doctors can safely perform necessary treatments without causing you pain or discomfort. Zyfol can also be used to keep patients sedated (calm and sleepy) in intensive care units when they are on breathing machines.

This medication is administered only by trained healthcare professionals in hospital settings as an injection into a vein. It is suitable for adults and children over one month of age requiring anesthesia, and for patients aged 16 years and older who need sedation while receiving mechanical ventilation in an ICU.

Before receiving Zyfol, inform your doctor about all medical conditions, allergies (especially to peanuts or soya), and medications you are taking. This ensures your anesthesia plan is safe and tailored to your individual health needs.

Key points

  • General anesthetic injection for surgical procedures and intensive care sedation
  • Administered intravenously by healthcare professionals only
  • Safe for adults and children over 1 month old
  • Contains soya oil—important for those with soya or peanut allergies

Therapeutic Uses

  • To induce general anesthesia for surgical operations and medical procedures
  • To maintain unconsciousness during extended surgical procedures
  • To sedate patients on breathing machines in intensive care units (age 16+)
  • To provide reversible loss of consciousness for diagnostic procedures

How it Works

Zyfol works by enhancing the activity of a natural brain chemical called GABA (gamma-aminobutyric acid) through specific receptors in the brain. This enhancement reduces electrical activity in the brain and decreases the flow of charged particles across nerve cells, resulting in unconsciousness and loss of awareness. The medication's effects are fully reversible, meaning normal consciousness returns once administration stops.

How to Take

Zyfol 20ml injection is administered exclusively in hospital settings by trained anesthesiologists or healthcare providers. It is given as an intravenous injection, typically into a vein in the back of your hand or forearm.

Instructions

  • Healthcare provider will assess your age, body weight, and medical condition to determine the correct dose
  • The injection will be administered slowly into a vein by a trained professional
  • Your vital signs (heart rate, blood pressure, oxygen levels) will be monitored throughout the procedure
  • You will gradually lose consciousness within seconds of administration

Timing

Administered only in hospital/surgical settings by qualified medical staff

Missed dose

Not applicable—Zyfol is administered by healthcare providers during scheduled procedures only

Overdose

Overdose can occur only if administration is not properly monitored. In hospital settings, medical staff continuously monitor dosing. If excessive sedation occurs, treatment will be adjusted immediately by your healthcare team

Side Effects

  • Low blood pressure and slow heart rate during and immediately after the procedure
  • Pain, redness, or irritation at the injection site where the IV is placed
  • Changes in breathing patterns, ranging from slower breathing to temporary breath-holding
  • Nausea, vomiting, or headache after waking from anesthesia
  • Allergic reactions including difficulty breathing, swelling of face/lips/eyelids, or body rash
  • Stress-related heart problems with symptoms like chest pain, irregular heartbeat, or shortness of breath

Safety Advice

Pregnancy

Unsafe

Zyfol can cross the placental barrier and potentially cause miscarriage, birth defects, or depression in newborns if used during pregnancy.

Tip: Inform your doctor if you are pregnant, think you may be pregnant, or are planning pregnancy. Zyfol will only be given if the doctor determines it is absolutely essential for your safety.

Breastfeeding

Unsafe

Zyfol can pass into breast milk and may cause sedation or depression in nursing infants.

Tip: Consult your doctor about the appropriate timing to resume breastfeeding after receiving Zyfol anesthesia. Your doctor will advise how long to wait before nursing is safe.

Liver

Consult Doctor

Zyfol is processed by the liver. In rare cases, it may cause liver enlargement. Patients with liver disease may require dose adjustments.

Tip: Inform your anesthesiologist if you have mild, moderate, or severe liver problems before your procedure. Your dosage may need adjustment based on liver function tests.

Kidney

Consult Doctor

While Zyfol is primarily metabolized by the liver, kidney function may affect overall drug clearance in patients with severe kidney disease.

Tip: Inform your doctor if you have kidney disease or are on dialysis before receiving this medication.

Lungs/Respiratory

Consult Doctor

Zyfol depresses respiratory function and must be used with caution in patients with severe breathing disorders or lung disease.

Tip: Inform your anesthesiologist if you have asthma, COPD, sleep apnea, or other active lung diseases. Breathing support may be necessary during your procedure.

Heart/Cardiovascular

Consult Doctor

Zyfol can lower blood pressure and slow heart rate. Patients with heart conditions require careful monitoring.

Tip: Inform your doctor if you have heart disease, high blood pressure, or low blood pressure before your procedure.

Alcohol

Unsafe

Combining alcohol with Zyfol significantly increases sedation and can cause dangerous breathing problems and excessive blood pressure reduction.

Tip: Do not drink alcohol before, during, or after your procedure until your doctor confirms the anesthetic effects have completely worn off and it is safe to resume.

Driving

Unsafe

Zyfol causes drowsiness and impairs coordination, concentration, and judgment. It can affect your ability to drive and operate machinery safely.

Tip: Do not drive, operate heavy machinery, or make important decisions until your doctor confirms the drowsy effects have completely resolved. Plan for someone to drive you home.

Allergies

Unsafe

Zyfol is unsafe for patients allergic to propofol or any ingredient in the formulation. The injection contains soya oil, making it unsuitable for soya or peanut allergies.

Tip: Inform your doctor immediately if you have allergies to propofol, soya, peanuts, or egg (as some formulations contain egg lecithin). Do not receive this medication if you have these allergies.

Special Conditions

Consult Doctor

Patients with seizure history, high blood fat levels, dehydration, mitochondrial disease, or prolonged illness may require special precautions with Zyfol.

Tip: Inform your anesthesiologist about any seizure disorders, high cholesterol, dehydration, or genetic/metabolic conditions before your procedure.

FAQs

How long does the effect of zyfol 20ml injection last?
Zyfol has a rapid onset, causing unconsciousness within 30-40 seconds. The duration of action is short—typically 5-10 minutes after a single dose—allowing quick recovery of consciousness. However, when given continuously in intensive care settings, patients remain sedated until the infusion is stopped. Full mental clarity and coordination typically return within 30-60 minutes after the medication is discontinued, though complete metabolic recovery may take several hours.
Is zyfol 20ml injection indicated for children?
Yes, Zyfol is indicated for children over one month of age for general anesthesia during surgical procedures. It is also approved for sedation in children aged 16 years and older who require ventilatory support in intensive care units. The dose is carefully calculated based on the child's age, body weight, and medical condition by the anesthesiologist to ensure safety and effectiveness.
What should I take before getting my zyfol 20ml injection?
Before Zyfol administration, follow your pre-operative fasting instructions given by your hospital (typically no food for 6-8 hours, and no liquids for 2 hours before surgery). Inform your anesthesiologist of all medications, supplements, and allergies. Wear comfortable, loose clothing and remove jewelry, dentures, and contact lenses. Avoid alcohol and sedative medications unless approved by your doctor. Your doctor may prescribe pre-medication to help you relax before the procedure.
What restrictions should I follow after a zyfol 20ml injection?
After receiving Zyfol, avoid driving, operating machinery, or making important decisions for at least 24 hours as drowsiness and impaired judgment may persist. Do not consume alcohol until completely recovered and your doctor approves. Rest at home and avoid strenuous activities. Have someone care for you at home if possible. Eat only light meals initially if nausea occurs. Report any persistent headache, dizziness, or unusual symptoms to your doctor immediately.
Can zyfol 20ml injection cause dependence?
Zyfol is not typically associated with dependency or addiction when used appropriately for single-dose anesthesia or short-term intensive care sedation. However, in rare cases of prolonged use in ICU settings, some children may experience withdrawal symptoms including unusual behavior, sweating, tremors, and anxiety when the medication is stopped. Your medical team monitors for these signs and adjusts discontinuation carefully to minimize withdrawal effects.
Can zyfol 20ml injection be taken orally?
No, Zyfol 20ml injection cannot be taken by mouth. It must be administered exclusively as an intravenous injection (directly into a vein) by trained healthcare professionals in a hospital or surgical facility. Oral administration would be ineffective and unsafe. Zyfol is designed and approved only for intravenous use under professional medical supervision with proper monitoring of vital signs.

Drug Interactions

Zyfol may interact with certain medications, potentially causing unwanted effects. Inform your anesthesiologist about all medications, supplements, and herbal products you are taking before your procedure to prevent dangerous interactions.

Major interactions

  • Rifampicin (antibiotic used for tuberculosis) – may reduce Zyfol effectiveness
  • CNS depressants (sedatives, opioids, alcohol) – may increase sedation and breathing difficulties
  • Blood pressure medications – may cause excessive blood pressure drop

Precautions

  • Disclose all prescription medications, over-the-counter drugs, and supplements
  • Inform your doctor if you take blood pressure or heart medications
  • Avoid alcohol consumption before and after your procedure
  • Report any herbal medicine or supplement use to your anesthesiologist

Important

Never consume alcohol or take additional sedative medicines unless your doctor specifically approves. Combining Zyfol with other depressants can cause serious breathing problems and dangerous drops in blood pressure.

Storage Details

🌡 Store below 25°C (77°F) in a cool environment

Keep in original vial or container; protect from direct light

  • Store in a dark place away from sunlight and UV exposure
  • Keep out of reach of children and pets
  • Do not freeze the medication
  • Store in hospital pharmacy under controlled conditions only

Fact Box

Active Ingredient
Propofol 20 mg/ml
Drug Class
General Anesthetic (Intravenous)
Therapeutic Use
Surgical anesthesia and intensive care sedation
Prescription Required
Yes
Route of Administration
Intravenous injection only
Suitable Age Group
Infants (1 month+) and adults; ICU sedation for ages 16+

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Quality Guaranteed

Guaranteed Temperature-Controlled Handling and Shipping — We maintain strict cold chain compliance for temperature-sensitive medicines from storage to delivery.

1

Carefully Packed

Every order is carefully packaged to maintain the required temperature for cold chain medicines and vaccines.

2

Verified Storage

Our pharmaceutical storage facilities are closely monitored and verified to ensure proper temperature conditions.

3

Insulated Shipping

We use insulated containers and temperature monitors for safe transport of temperature-sensitive medicines.

Rx Prescription Required

This medicine requires a valid prescription from a registered medical practitioner (doctor). As per Indian regulations, prescription-only medicines cannot be sold without a valid Rx.

You will need to upload your prescription during checkout. We accept clear images or PDF of your doctor's prescription.

Consult your doctor before taking any medicine. Never self-medicate with prescription drugs.

Medical Disclaimer

MedsRight is committed to providing consumers with reliable, accurate, and expert-validated healthcare information. All content published on this website is intended solely for general informational and educational purposes. It should not be considered a substitute for professional medical advice, diagnosis, or treatment.

We strongly encourage you to consult a qualified doctor or healthcare professional for guidance regarding any medical condition, symptoms, or medications. Never ignore or postpone seeking professional medical advice because of information you have read on MedsRight.

Our goal is to empower patients with trustworthy information while fully respecting and preserving the integrity of the doctor–patient relationship.

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